ABL tyrosine kinases

ABL 酪氨酸激酶

英文解释

ABL tyrosine kinases are a family of non-receptor tyrosine kinases (nRTKs) consisting of two paralogs, ABL1 and ABL2. ABL1 and ABL2 both promote tumor progression and metastasis. ABL kinases regulate diverse cellular processes such as inflammation, cancer and other pathologies.

中文解释

ABL 酪氨酸激酶是一个非受体酪氨酸激酶 (nRTK) 家族，由两个旁系同源物 ABL1 和 ABL2 组成。ABL1 和 ABL2 均促进肿瘤进展和转移。ABL 激酶调节多种细胞过程，例如炎症、癌症和其他病理。

参考文献

[1]. Khatri A, et al. Multifunctional Abl kinases in health and disease. J Cell Sci. 2016 Jan 1;129(1):9-16.