Antisense oligonucleotide (ASOs)

反义寡核苷酸 (ASO)

英文解释

Antisense oligonucleotides (ASOs) are short, synthetic, single-stranded oligodeoxynucleotides that can alter RNA and reduce, restore, or modify protein expression.

中文解释

反义寡核苷酸 (ASO) 是短的、合成的、单链的寡脱氧核苷酸，可以改变 RNA ，并减少、恢复或改变蛋白质表达。

参考文献

[1]. Rinaldi C, et al. Antisense oligonucleotides: the next frontier for treatment of neurological disorders. Nat Rev Neurol. 2018 Jan;14(1):9-21.