Arachidonate 5-lipoxygenase (5-LOX)

花生四烯酸5-脂氧合酶

英文解释

Arachidonate 5-lipoxygenase (ALOX5), an immune-responsive metabolic enzyme expressed in neutrophils, macrophages, and dendritic cells, generates lipid mediators (LMs) during post-myocardial infarction healing.

中文解释

花生四烯酸 5-脂氧合酶 (ALOX5) 是一种在中性粒细胞、巨噬细胞和树突状细胞中表达的免疫反应性代谢酶，在心肌梗死后愈合过程中产生脂质介质 (LM)。

参考文献

[1]. Ganesh V Halade, et al. Arachidonate 5-lipoxygenase is essential for biosynthesis of specialized pro-resolving mediators and cardiac repair in heart failure. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H721-H737.