Arginine vasopressin (AVP)/Antidiuretic hormone (ADH)/Vasopressin

精氨酸加压素/抗利尿激素/加压素

英文解释

Arginine vasopressin (AVP), also known as Vasopressin or antidiuretic hormone (ADH), is a nonapeptide synthesized in the hypothalamus. AVP is the major physiological regulator of renal water excretion and blood volume. AVP is synthesized in the neurosecretory cells of the supraoptic and paraventricular nuclei of the hypothalamus and stored in neurosecretory granules in the posterior pituitary gland. AVP plays essential roles in the control of the body’s osmotic balance, blood pressure regulation, sodium homeostasis, and kidney functioning.

中文解释

精氨酸加压素 (AVP)/抗利尿激素 (ADH)/加压素，是一种在下丘脑中合成的九肽。AVP 是肾水排泄和血容量的主要生理调节剂。AVP 在下丘脑视上核和室旁核的神经分泌细胞中合成，并储存在垂体后叶的神经分泌颗粒中。AVP 在控制身体的渗透平衡、血压调节、钠稳态和肾功能方面发挥着重要作用。

参考文献

[1]. Natig Gassanov, et al. Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH). Eur J Clin Pharmacol. 2011 Apr;67(4):333-346.
[2]. Cuzzo B Sandeep A, et al. Physiology, Vasopressin. Study Guide from StatPearls Publishing, Treasure Island (FL), 26 Sep 2018.