Branched-chain amino acid aminotransferase (BCAT)

支链氨基酸转氨酶

英文解释

Branched-chain amino acid aminotransferases (BCATs) catalyze reversible stereoselective transamination of branched-chain amino acids (BCAAs) L-leucine, L-isoleucine, and L-valine. BCATs are the key enzymes of BCAA metabolism in all organisms. The catalysis proceeds through the ping-pong mechanism with the assistance of the cofactor pyridoxal 5'-phosphate (PLP).

中文解释

支链氨基酸转氨酶 (BCATs) 催化可逆的支链氨基酸 (BCAAs) L-亮氨酸、L-异亮氨酸和 L-缬氨酸的立体选择性转氨化。BCATs 是所有生物体内 BCAA 代谢的关键酶。在辅因子吡哆醛 5'-磷酸 (PLP) 的辅助下，催化通过 ping-pong 机制进行。

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