Bruton’s tyrosine kinase (BTK)

发布时间:2023-03-22 22:08:39 浏览次数:37
Bruton’s tyrosine kinase (BTK)

布鲁顿酪氨酸激酶

英文解释

Bruton's tyrosine kinase (BTK) is a TEC kinase with a multifaceted role in B-cell biology and function, highlighted by its position as a critical component of the B-cell receptor signalling pathway. Bruton's tyrosine kinase (BTK)acts asa driving factor not only in lymphoproliferative disorders but also in autoimmune diseases and response to infection.

中文解释

布鲁顿酪氨酸激酶 (BTK),是一种 TEC 激酶,在 B 细胞生物学和功能中具有多方面的作用,尤其是作为B 细胞受体信号通路的关键成分。布鲁顿酪氨酸激酶,不仅在淋巴增生性疾病中起驱动作用,而且在自身免疫性疾病和对感染的反应中也起驱动作用。

参考文献

[1]. McDonald C, et al. The role of Bruton's tyrosine kinase in the immune system and disease. Immunology. 2021 Dec;164(4):722-736.
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