Carnitine palmitoyltransferase1 (CPT1)

肉碱棕榈酰转移酶 1

英文解释

Carnitine palmitoyltransferase1is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Carnitine palmitoyltransferase1shows 3 isoform including liver, brain, and muscle isoforms.

中文解释

肉碱棕榈酰转移酶 1 (CPT1) 是肉碱依赖性跨线粒体内膜转运的关键酶，其缺乏导致脂肪酸-氧化率降低。肉碱棕榈酰转移酶1有肝脏型、脑型和肌肉型3种亚型。

参考文献

[1]. IJlst L, et al. Molecular basis of hepatic carnitine palmitoyltransferase I deficiency. J Clin Invest. 1998 Aug 1;102(3):527-31.