Long noncoding RNA (lncRNA)

长链非编码 RNA

英文解释

Long noncoding RNAs (lncRNAs) are pervasively transcribed and critical regulators of the epigenome. lncRNA does not code for proteins, but function directly as RNAs, recruiting chromatin modifiers to mediate transcriptional changes in processes ranging from X-inactivation (XIST) to imprinting (H19).

中文解释

长链非编码 RNA (lncRNA) 是普遍转录的表观基因组的关键调节因子。lncRNA 不编码蛋白质，直接作为 RNA 发挥作用，招募染色质修饰剂来介导从 X 失活 (XIST) 到印记 (H19) 的过程中的转录变化。

参考文献

[1]. Tiffany Hung, et al. Long noncoding RNA in genome regulation: prospects and mechanisms. RNA Biol. 2010 Sep-Oct;7(5):582-5.