Low density lipoprotein receptor (LDLR)

低密度脂蛋白受体

英文解释

Low density lipoprotein receptor (LDLR) is responsible for uptake of cholesterol-carrying lipoprotein particles into cells. The receptor binds lipoprotein particles at the cell surface and releases them in the low-pH environment of the endosome.

中文解释

低密度脂蛋白受体 (LDLR) 负责将携带胆固醇的脂蛋白颗粒吸收到细胞中。受体结合在细胞表面的脂蛋白颗粒，并在核内体的低 pH 环境中释放它们。

参考文献

[1]. Jeon H, Blacklow SC. Structure and physiologic function of the low-density lipoprotein receptor. Annu Rev Biochem. 2005;74:535-62.