Lymphocyte-oriented kinase (LOK)

淋巴细胞导向激酶

英文解释

Lymphocyte-oriented kinase (LOK) is a member of the STE20/p21-activated kinase (PAK) family and expressed predominantly in lymphoid organs. LOKis potentially involved in the regulation of LFA-1-mediated lymphocyte adhesion.

中文解释

淋巴细胞导向激酶 (LOK) 是 STE20/p21 激活激酶 (PAK) 家族的一员，主要在淋巴器官中表达。LOK 可能参与了 LFA-1 介导的淋巴细胞粘附的调节。

参考文献

[1]. Endo J, et al. Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes. FEBS Lett. 2000 Feb 25;468(2-3):234-8.