Neuraminidase (NA)

神经氨酸酶

英文解释

Neuraminidase (NA), also known as sialidase, is a glycoprotein distributed on the membrane of influenza virus. It can catalyze the hydrolysis of sialic acid. Neuraminidase also significantly deglycosylated and degraded lysosomal associated membrane proteins, inducing lysosomal rupture.

中文解释

神经氨酸酶 (NA)，又称唾液酸酶是分布于流感病毒被膜上的一种糖蛋白，可以催化唾液酸水解。神经氨酸酶还显著地去糖基化和降解溶酶体相关的膜蛋白，诱导溶酶体破裂。

参考文献

[1]. Zhang JY, et al. Neuraminidase 1 and its Inhibitors from Chinese Herbal Medicines: An Emerging Role for Cardiovascular Diseases. Am J Chin Med. 2021;49(4):843-862.
[2]. Ju X, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015 Oct;89(20):10347-58.