Non Small Cell Lung Cancer (NSCLC)

非小细胞肺癌

英文解释

Non Small Cell Lung Cancer (NSCLC) acounts for approximately 85% of all new lung cancer diagnoses. NSCLC are divided into squamous cell carcinomas, adenocarcinomas, and large-cell carcinomas. NSCLC has the occurrence of histological transformation to small cell lung cancer (SCLC), which is accompanied by resistance to the original tyrosine kinase inhibitors (TKIs).

中文解释

非小细胞肺癌 (NSCLC) 约占所有新确诊肺癌 (lung cancer) 病例的 85%。NSCLC 分为鳞状细胞癌、腺癌和大细胞癌。NSCLC 中会发生组织学转化为小细胞肺癌 (SCLC)，并伴有对原酪氨酸激酶抑制剂 (TKI) 的耐药性。

参考文献

[1]. Rath B, et al. Non-small cell lung cancer-small cell lung cancer transformation as mechanism of resistance to tyrosine kinase inhibitors in lung cancer. Cancer Drug Resist. 2020 Feb 28;3(2):171-178.