The B cell activating factor (BAFF)/B lymphocyte stimulator (BLyS)

B 细胞激活因子/B 淋巴细胞刺激因子

英文解释

The B cell activating factor (BAFF)/B lymphocyte stimulator (BLyS), is a B cell survival factor which supports autoreactive B cells and prevents their deletion. BAFF expression is closely linked with autoimmunity and is enhanced by genetic alterations and viral infections.

中文解释

B 细胞激活因子 (BAFF)/B 淋巴细胞刺激因子 (BLyS) 是一种 B 细胞存活因子，可支持自身反应性 B 细胞并防止其缺失。 BAFF 表达与自身免疫密切相关，并因基因改变和病毒感染而增强。

参考文献

[1]. Tamara M?ckel, et al. B cell activating factor (BAFF): Structure, functions, autoimmunity and clinical implications in Systemic Lupus Erythematosus (SLE). Autoimmun Rev. 2021 Feb;20(2):102736.