The HER-2 receptor tyrosine kinase

HER-2受体酪氨酸激酶

英文解释

The HER-2 receptor tyrosine kinase is an important regulator of cell proliferation and survival, and it is a target of therapeutic intervention for HER-2 positive breast cancer.

中文解释

HER-2受体酪氨酸激酶是细胞增殖和存活的重要调节因子，是 HER-2 阳性乳腺癌治疗干预的靶点。

参考文献

[1]. Xiangdong Liu, et al. Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab. Cancer Biol Ther. 2006 Jun;5(6):648-56.