The renin-angiotensin-aldosterone system (RAAS)

肾素-血管紧张素-醛固酮系统

英文解释

The renin-angiotensin-aldosterone system (RAAS) is a cardiovascular circulating hormonal system. RAAS plays a fundamental role in the physiology of blood pressure control and the pathophysiology of hypertension (HTN) with effects on vascular tone, sodium retention, oxidative stress, fibrosis, sympathetic tone, and inflammation.

中文解释

肾素-血管紧张素-醛固酮系统(RAAS)是一种心血管循环激素系统。RAAS在血压控制生理学和高血压(HTN)的病理生理学中起着重要作用，影响血管张力、钠潴留、氧化应激、纤维化、交感神经张力和炎症。

参考文献

[1]. A Mascolo, et al. New and old roles of the peripheral and brain renin-angiotensin-aldosterone system (RAAS): Focus on cardiovascular and neurological diseases. Int J Cardiol. 2017 Jan 15;227:734-742.
[2]. Lama Ghazi, et al. Advances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy. F1000Res. 2017 Mar 21;6:F1000 Faculty Rev-297.