The retinoblastoma susceptibility gene (RB1)

视网膜母细胞瘤易感基因

英文解释

The retinoblastoma susceptibility gene (RB1) is important in normal development, gene transcription, DNA replication, repair, and mitosis. RB1 dysfunction in retinoblasts is the main cause of retinoblastoma

中文解释

视网膜母细胞瘤易感基因 (RB1) 在正常发育、基因转录、DNA 复制、修复和有丝分裂中起着重要功能。视网膜母细胞中的 RB1 功能障碍是视网膜母细胞瘤 (retinoblastoma) 的主要原因>

参考文献

[1]. Viana MC, et al. The human retinoblastoma susceptibility gene (RB1): an evolutionary story in primates. Mamm Genome. 2017 Jun;28(5-6):198-212.