The Toll/interleukin-1 (IL-1) receptor (TIR)

Toll/白细胞介素-1 (IL-1) 受体 (TIR)

英文解释

The Toll/interleukin-1 (IL-1) receptor (TIR) family comprises two groups of transmembrane proteins: the IL-1 receptor (IL-1R) subfamily and the Toll-like receptor (TLR) subfamily. The Toll/IL-1 receptor (TIR) domain is required for initiating intracellular signaling.

中文解释

Toll/白细胞介素-1 (IL-1) 受体 (TIR) 家族包含两组跨膜蛋白：IL-1 受体 (IL-1R) 亚家族和 Toll 样受体 (TLR) 亚家族。Toll/IL-1 受体 (TIR) 结构域是启动细胞内信号传导所必需的。

参考文献

[1]. Michael U Martin, et al. Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family. Biochim Biophys Acta. 2002 Nov 11;1592(3):265-80.