The tuberous sclerosis complex 1/2 (TSC1/2)

结节性硬化复合物 1/2

英文解释

The tuberous sclerosis complex 1/2 (TSC1/2) is a negative regulator of the nutrient-sensing kinase mechanistic target of rapamycin complex (mTORC1), and its function is generally associated with tumor suppression.

中文解释

结节性硬化复合物 1/2 (TSC1/2) 是雷帕霉素复合物 (mTORC1) 的营养敏感激酶机制靶标的负调节因子，其功能通常与肿瘤抑制有关。

参考文献

[1]. G?tz Hartleben, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018 Nov 2;37(21):e98589.