The β2 adrenergic receptor (ADRB2)

β2 肾上腺素能受体

英文解释

The β2 adrenergic receptor (ADRB2) is a G protein-coupled transmembrane receptor located on airway smooth muscle cells. ADRB2 activation causes smooth muscular relaxation in response to endogenous catecholamines. ADRB2 is an important regulator of airway smooth muscle tone.

中文解释

β2 肾上腺素能受体 (ADRB2) 是一种位于气道平滑肌细胞上的 G 蛋白偶联跨膜受体。ADRB2 激活导致平滑肌松弛以响应内源性儿茶酚胺。ADRB2 是气道平滑肌张力的重要调节剂。

参考文献

[1]. M Thomsen, et al. β2-adrenergic receptor polymorphisms, asthma and COPD: two large population-based studies. Eur Respir J. 2012 Mar;39(3):558-66.