TNF related apoptosis-inducing ligand receptor 1 (TRAIL-R1)

TNF 相关凋亡诱导配体受体 1 (TRAIL-R1)

英文解释

Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL-R1) is a potent endogenous activator of the cell death pathway and functions by activating the cell surface death receptors 4 and 5 (DR4 and DR5).

中文解释

肿瘤坏死因子相关凋亡诱导配体?1 (TRAIL-R1)?是一种有效的细胞死亡途径内源性激活剂，通过激活细胞表面死亡受体?4?和?5（DR4?和?DR5）发挥作用。

参考文献

[1]. Chinnaiyan AM, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1754-9.