Vascular endothelial growth factor receptor (VEGFR)

血管内皮生长因子受体

英文解释

Vascular endothelial growth factor receptor (VEGFR) is membrane-bound receptor tyrosine kinase proteins that are frequently overexpressed in many cancers. VEGFR bind to vascular endothelial growth factors (VEGFs) to elicit various downstream effects.

中文解释

血管内皮生长因子受体 (VEGFR) 是膜结合受体酪氨酸激酶蛋白，在许多癌症中经常过度表达。VEGFR 与 血管内皮生长因子 结合以引发各种下游效应。

参考文献

[1]. Sinem Karaman, et al. Vascular endothelial growth factor signaling in development and disease. Development. 2018 Jul 20;145(14):dev151019.
[2]. Nichole E M Kaufman, et al. Molecular Targetingof Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial GrowthFactor Receptor (VEGFR). Molecules. 2021 Feb 18;26(4):1076.