Voltage-gated proton channel (HV1)

电压门控质子通道

英文解释

The voltage-gated proton channel Hv1 is made of two voltage-sensing domains (VSDs) and lacks the pore domain (PD). The voltage-gated proton channel HV1 is a ion channel that rapidly removes protons from depolarized cytoplasm and is highly expressed in the immune system.

中文解释

电压门控质子通道 (HV1) 由两个 voltage-sensing 域 (VSDs) 组成，缺少 pore 域 (PD)。电压门控质子通道 HV1 是一种离子通道，能迅速从去极化的细胞质中移除质子，在免疫系统中高度表达。

参考文献

[1]. Wu L-J. et al. Voltage-Gated Proton Channel HV1 in Microglia. The Neuroscientist. 2014;20(6):599-609.
[2]. Liang Hong, et al. Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains. Neuron. 2013 Jan 23;77(2):274-87.