Yes-associated protein (YAP)

Yes 相关蛋白

英文解释

Yes-associated protein (YAP) is a key transcription factor in the Hippo signaling pathway. YAP is an oncoprotein located in the cytoplasm in an inactive form, and when activated, it translocates to the nucleus and activates the transcription of genes responsible for cell division and apoptosis.

中文解释

Yes 相关蛋白 (YAP) 是 Hippo 信号通路中的关键转录因子。YAP 是一种以非活性形式存在于细胞质中的癌蛋白，当被激活时，它易位到细胞核并激活负责细胞分裂和凋亡的基因的转录。

参考文献

[1]. Abylkassov R, et al. Role of Yes-associated protein in cancer: An update. Oncol Lett. 2016 Oct;12(4):2277-2282.