β-Adrenergic receptors (βARs)

β-肾上腺素能受体

英文解释

β-Adrenergic receptors (βARs) belong to a large family of cell surface receptors known as G protein-coupled receptors (GPCRs). βARs are coupled to Gs protein (Gαs) for the activation of adenylyl cyclase (AC) yielding cyclic AMP (CAMP), which can affect the cardiac function such as injury.

中文解释

β-肾上腺素能受体 (βAR) 属于称为 G 蛋白偶联受体 (GPCR) 的一大类细胞表面受体。 βARs 与 Gs 蛋白 (Gαs) 偶联用于激活腺苷酸环化酶 (AC) 产生环 AMP (CAMP)，这会影响心脏功能，例如损伤。

参考文献

[1]. Daniel Chikere Ali, et al. β-Adrenergic receptor, an essential target in cardiovascular diseases. Heart Fail Rev. 2020 Mar;25(2):343-354.