7-Methylguanosine

A methylated form of guanosine

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥1100.00

880.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

7-Methylguanosine is a methylated form of the purine nucleoside guanosine . It is an RNA modification that is present in the 5’-terminal cap of mRNA, where it promotes translation, as well as in tRNA, where it stabilizes the tRNA structure.^1,2 7-Methylguanosine has been used as a substrate to measure the activity of purine nucleoside phosphorylase (PNP).³ Urinary 7-methylguanosine levels are decreased in patients with prostate cancer.¹

1.Fernández-Peralbo, M.A., Gómez-Gómez, E., Calderón-Santiago, M., et al.Prostate cancer patients-negative biopsy controls discrimination by untargeted metabolomics analysis of urine by LC-QTOF: Upstream information on other omicsSci. Rep.638243(2016) 2.Tomikawa, C.7-Methylguanosine modifications in transfer RNA (tRNA)Int. J. Mol. Sci.19(12)4080(2018) 3.Stachelska-Wierzchowska, A., and Wierzchowski, J.Non-typical nucleoside analogs as fluorescent and fluorogenic indicators of purine-nucleoside phosphorylase activity in biological samplesAnal. Chim. Acta1139119-128(2020)