Remdesivir nucleoside monophosphate 是 Remdesivir 的代谢产物。Remdesivir 是一种具有抗 SARS-CoV 和 MERS-CoV 活性的核苷类似物。
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Remdesivir nucleoside monophosphate is a metabolite of Remdesivir[1]. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV[2].
[1]. Byoung Kwon Chun, et al. or treating filoviridae virus infections. US20160122374. [2]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.
DMNPE-caged ATP diammonium salt
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