PtdIns-(4,5)-P2-fluorescein (triethylammonium salt)

A neuropeptide with diverse biological activities

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库存: 现货

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10ug

￥1425.00

1140.00

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25ug

￥3400.00

2720.00

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50ug

￥6375.00

5100.00

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100ug

￥11337.00

9070.00

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Background

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.^1,2 PtdIns-(4,5)-P₂-fluorescein is a fluorescent probe for any protein with a high-affinity binding interaction with inositol-(4,5)-triphosphate phospholipids, such as PI3K, PTEN, or PH-domain-containing proteins.

1.Exton, J.H.Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteinsAnnu. Rev. Pharmacol. Toxicol.36481-509(1996) 2.Majerus, P.W.Inositol phosphate biochemistryAnnu. Rev. Biochem.61225-250(1992)