BRL 15572 hydrochloride

A 5-HT1D receptor antagonist

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10mg

￥3212.00

2570.00

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50mg

￥13212.00

10570.00

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Background

A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.

Hagan et al (1997) Stimulation of 5-HT1B receptors causes hypothermia in the rat. Eur.J.Pharmacol. 331 169 PMID:9274976 |Price et al (1997) SB-216641 and BRL-15572 - compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 312 PMID:9303567 |Saxena et al (1998) 5-HT1-like receptors: a time to bid goodbye. TiPS 19 311 PMID:9745358 |Schlicker et al (1997) Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 321 PMID:9303568