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  • Desmethylnortriptyline
Desmethylnortriptyline的可视化放大

Desmethylnortriptyline

Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢产物,用于缓解抑郁症症状。

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Desmethylnortriptyline的二维码
  • 库存: 现货
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  • 5mg
    ¥5937.00
    4750.00
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  • 10mg
    ¥10250.00
    8200.00
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  • 货号: ajcx29278
  • CAS: 4444-42-2
  • 别名: 去甲基去甲替林
  • 分子式: C18H19N
  • 分子量: 249.35
  • 纯度: >98%
  • 溶解度:
  • 储存: Store at -20°C
  • 库存: 现货

Background

Desmethylnortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].



[1]. Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4. [2]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

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