Fipronil

An insecticide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥1100.00

880.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajcx29346
CAS: 120068-37-3
别名: 氟虫腈
分子式: C12H4Cl2F6N4OS
分子量: 437.15
纯度: >98%
溶解度: DMSO: 250 mg/mL (571.89 mM)
储存: 4°C, protect from light, stored under nitrogen
库存: 现货

Background

Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC₅₀s = 30 and 1,600 nM for cockroach and rat receptors, respectively).¹ It also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC₅₀s = 800 and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.² Formulations containing fipronil have been used as insecticides in veterinary care.

1.Narahashi, T., Zhao, X., Ikeda, T., et al.Glutamate-activated chloride channels: Unique fipronil targets present in insects but not in mammalsPestic. Biochem. Physiol.97(2)149-152(2010) 2.Caballero, M.V., Ares, I., Martínez, M., et al.Fipronil induces CYP isoforms in ratsFood Chem. Toxicol.83215-221(2015)