Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. Gap 26 blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
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Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. Gap 26 blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
[1] A T Chaytor, et al. J Physiol. 1997 Aug 15;503 ( Pt 1)(Pt 1):99-110. [2] Katleen Braet, et al. Cell Calcium. 2003 Jan;33(1):37-48.
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