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  • Tenoxicam
Tenoxicam的可视化放大

Tenoxicam

An NSAID and COX-1 inhibitor

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  • 货号: ajci4254
  • CAS: 59804-37-4
  • 别名: 替诺昔康; Ro-12-0068
  • 分子式: C13H11N3O4S2
  • 分子量: 337.37832
  • 纯度: >98%
  • 溶解度: ≥ 10.5mg/mL in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.


Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID)[1].


Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia[2].


参考文献:
[1]. Ozgocmen, S., et al., In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci, 2005. 35(2): p. 137-43.
[2]. Galvao, R.I., et al., Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats. Neurochem Res, 2005. 30(1): p. 39-46.

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