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  • Acemetacin
Acemetacin的可视化放大

Acemetacin

An NSAID

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Acemetacin的二维码
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  • 货号: ajci5150
  • CAS: 53164-05-9
  • 别名: 阿西美辛; TVX 1322
  • 分子式: C21H18ClNO6
  • 分子量: 415.82
  • 纯度: >98%
  • 溶解度: ≥ 20.791mg/mL in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.


Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin. From Wikipedia.


参考文献:
[1]. Tavares IA, et al. Non-steroidal anti-inflammatory drugs that cause relatively little gastric damage. J Gastroenterol Hepatol. 1998 Nov;13(S3):S190-S192.

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