SNOG

An S-nitrosothiol NO donor

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库存: 现货

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促销价

数量
1mg

￥237.00

190.00

- +
5mg

￥650.00

520.00

- +
10mg

￥1037.00

830.00

- +
50mg

￥3050.00

2440.00

- +
100mg

￥4312.00

3450.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.[1][2][3][4]

Reference:
[1]. Radomski, M.W., Rees, D.D., Dutra, A., et al. S-Nitroso-glutathione inhibits platelet activation in vitro and in vivo. Br. J. Pharmacol. 107(3), 745-749 (1992).
[2] Butler, A.R., and Rhodes, P. Chemistry, analysis, and biological roles of S-nitrosothiols. Anal. Biochem. 249(1), 1-9 (1997).
[3]. Gasco, A., Fruttero, R., and Sorba, G. NO-donors: An emerging class of compounds in medicinal chemistry. Farmaco 51(10), 617-635 (1996).
[4]. Cook, J.A., Kim, S.Y., Teague, D., et al. Convenient colorimetric and fluorometric assays for S-nitrosothiols. Anal. Biochem. 238(2), 150-158 (1996).