Sulfamethazine

A sulfonamide antibacterial

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库存: 现货

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10mg

￥675.00

540.00

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100mg

￥4500.00

3600.00

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货号: ajci8810
CAS: 57-68-1
别名: 磺胺二甲嘧啶; Sulfadimidine; Sulfadimerazine
分子式: C12H14N4O2S
分子量: 278.33
纯度: >98%
溶解度: ≥ 9.9mg/mL in DMSO
储存: Store at -20°C
库存: 现货

Background

Sulfamethazine (Sulfadimidine) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine in animal product is set at 100 μg/kg[1][2].

Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC0->∞, significantly increases t1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01[1].

参考文献:
[1]. VAN Poucke LSG, et al. Pharmacokinetics and Tissue Residues of Sulfathiazole and Sulfamethazine in Pigs. J Food Prot. 1994 Sep;57(9):796-801.
[2]. Sheng Y J, et al. Production of chicken yolk IgY to sulfamethazine: comparison with rabbit antiserum IgG. Food and Agricultural Immunology. 2015, 26(3):305-316.