Flubendazole

An anthelmintic

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库存: 现货

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50mg

￥625.00

500.00

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货号: ajci10662
CAS: 31430-15-6
别名: 氟苯咪唑
分子式: C16H12FN3O3
分子量: 313.28
纯度: >98%
溶解度: ≥ 10.71mg/mL in DMSO with gentle warming
储存: Store at -20°C
库存: 现货

Background

Flubendazole is a safe and efficacious anthelmintic drug, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].

参考文献:
[1]. Michaelis M, et al. Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen. Sci Rep. 2015 Feb 3;5:8202.
[2]. Zhou X, et al. Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis. Cell Death Discov. 2018 Feb 14;4:18.