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CK 666的可视化放大

CK 666

An Arp2/3 inhibitor

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CK 666的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 5mg
    ¥762.00
    610.00
    - +
  • 10mg
    ¥1350.00
    1080.00
    - +
  • 50mg
    ¥5450.00
    4360.00
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  • 货号: ajci12362
  • CAS: 442633-00-3
  • 别名:
  • 分子式: C18H17FN2O
  • 分子量: 296.34
  • 纯度: >98%
  • 溶解度: <29.63mg/ml in DMSO; <29.63mg/ml in ethanol
  • 储存: Store at -20°C
  • 库存: 现货

Background

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1].


参考文献:
[1]. Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20(5):701-12.

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