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Background:
Isovaleramide is an active principle on central nervous system from Valeriana pavonii, as an anticonvulsant.Target:in vitro: Isovaleramide (300 μM) exhibits a 42% of inhibition of the binding of 3H-FNZ to its sites.in vivo: Isovaleramide at 100 mg/Kg, p.o, evidences a 90% index protection against the maximal electroshock seizure in mice (MES).
LX1606 Hippurate (Telotristat etiprate)
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