Bethanechol chloride

A muscarinic acetylcholine receptor agonist

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50mg

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货号: ajci13080
CAS: 590-63-6
别名: 氯贝胆碱; Carbamyl-β-methylcholine chloride
分子式: C7H17N2O2.Cl
分子量: 196.68
纯度: >98%
溶解度: ≥ 9.834mg/mL in Water
储存: Store at -20°C
库存: 现货

Background

Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.Target: mAChRBethanechol Chloride (Carbamyl-β-methylcholine chloride) is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine, Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is not hydrolyzed by cholinesterase and will therefore have a long duration of action. Oral bethanechol significantly improves contraction pressures and bolus transit in the smooth muscle portion of the esophagus in patients with severe IEM [1]. Bethanechol Chloride (Carbamyl-β-methylcholine chloride) has potential benefit in the treatment of cerebral palsy [2].

参考文献:
[1]. Agrawal, A., et al., Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility. J Clin Gastroenterol, 2007. 41(4): p. 366-70.
[2]. Carter, W.J., Unexpected benefits of bethanechol in adults with cerebral palsy. Med J Aust, 2008. 189(5): p. 293.