Thymidine

A pyrimidine nucleoside

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库存: 现货

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5g

￥412.00

330.00

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10g

￥725.00

580.00

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25g

￥1362.00

1090.00

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货号: ajci15872
CAS: 50-89-5
别名: 胸苷; DThyd; NSC 21548
分子式: C10H14N2O5
分子量: 242.2
纯度: >98%
溶解度: ≥ 24.2mg/mL in DMSO with gentle warming, ≥ 53.6 mg/mL in Water, ≥ 3.75 mg/mL in EtOH with ultrasonic
储存: Store at 0-6°C
库存: 现货

Background

Thymidine, also named as deoxythymidine, deoxyribosylthymine and thymine deoxyriboside, is a pyrimidine deoxynucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. Thymidine is the DNA nucleoside T paired with deoxyadenosine (A) in DNA double helix. In cell biology it has been used to synchronize the cells in G1/early S phase. Thymidine occurs almost exclusively in DNA but it also occurs in the T-loop of tRNA. Thymidine is non-toxic and as part of one of the four nucleosides in DNA it is a naturally occurring compound existed in organisms and DNA viruses [1]. Thymidine is a nucleoside composed of a pentose sugar, deoxyribose, and a pyrimidine base thymine. Phosphorylation of thymidine with one, two or three phosphoric acid groups, can form dTMP (deoxythymidine monophosphate), dTDP, or dTTP. The molecular weight of thymidine is 242.229 u. The melting point is 185°C.

胸腺嘧啶，也称脱氧胸腺嘧啶、脱氧胸腺嘧啶核苷和胸腺嘧啶脱氧核糖核苷，是一种嘧啶脱氧核苷，由嘧啶碱基连接到脱氧核糖上组成。在DNA双螺旋结构中，胸腺嘧啶与脱氧腺嘌呤（A）配对。在细胞生物学中，它已被用于将细胞同步在G1 /早期S期。胸腺嘧啶几乎完全存在于DNA中，但也存在于tRNA的T环中。胸腺嘧啶是一种无毒的核苷，是DNA中四种核苷酸之一，是存在于生物体和DNA病毒中的天然化合物[1]。胸腺嘧啶是由脱氧核糖和嘧啶碱基组成的核苷。胸腺嘧啶与一个、两个或三个磷酸基团的磷酸化可以形成dTMP（脱氧胸腺嘧啶单磷酸）、dTDP或dTTP。胸腺嘧啶的分子量为242.229u。熔点为185℃。

Reference:
[1] Meng S, Maragakis P, Papaloukas C, et al.? DNA nucleoside interaction and identification with carbon nanotubes[J]. nano letters, 2007, 7(1): 45-50.