Neostigmine Bromide

溴化新斯的明是一种胆碱酯酶抑制剂，用于治疗重症肌无力。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
100mg

￥575.00

460.00

- +
500mg

￥1050.00

840.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci16354
CAS: 114-80-7
别名: 溴化新斯的明; Eustigmin bromide; Neoserine bromide
分子式: C12H19N2O2.Br
分子量: 303.2
纯度: >98%
溶解度: ≥ 15.16mg/mL in Water
储存: Store at -20°C, protect from light
库存: 现货

Background

Neostigmine bromide is a reversible inhibitor of acetylcholinesterase.[1]

AChE (acetylcholinesterase) is a hydrolase that hydrolyzes the neurotransmitter acetylcholine at the neuromuscular junction and cholinergic synaspe. It terminates the signal transductions and plays a role in neuronal apoptosis.

Neostigmine bromide is a quaternary amine that blocked cholinesterase activity to extend and enhance the muscarinic and nicotinic effects of acetylcholine. It is implicated for the treatment of primary open-angle glaucoma, postoperative urinary retention, paralytic ileus, myasthenia gravis etc. It is also reported to be an adjuvant to local anaesthetics and opioids for post-surgical pain after gynaecological or abdominal surgery. [1]

Reference:
[1] El-Kosasy AM, Nebsen M, Abd El-Rahman MK, Salem MY, El-Bardicy MG.? Comparative study of 2-hydroxy propyl beta cyclodextrin and calixarene as ionophores in potentiometric ion-selective electrodes for neostigmine bromide.? Talanta. 2011 Aug 15;85(2):913-8.?