Fesoterodine Fumarate

A muscarinic acetylcholine receptor antagonist

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥537.00

430.00

- +
10mg

￥750.00

600.00

- +
50mg

￥2437.00

1950.00

- +
1g

￥5712.00

4570.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci16416
CAS: 286930-03-8
别名: 富马酸非索罗定
分子式: C30H41NO7
分子量: 527.65
纯度: >98%
溶解度: Methanol: Slightly Soluble,Water: Slightly Soluble
储存: Store at -20°C
库存: 现货

Background

Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.IC50 value:Target: mAChRFesoterodine has the advantage of allowing more flexible dosage than other muscarinic antagonists. Its tolerability and side effects are similar to other muscarinic antagonists and as a new drug seems unlikely to make great changes in practices of treatment for overactive bladder.

参考文献:
[1]. Staskin David; Khullar Vik; Michel Martin C et al. Effects of voluntary dose escalation in a placebo-controlled, flexible-dose trial of fesoterodine in subjects with overactive bladder. Neurourology and urodynamics (2011), 30(8), 1480-5.
[2]. Vella Maria; Cardozo Linda Review of fesoterodine. Expert opinion on drug safety (2011), 10(5), 805-8.
[3]. Malhotra Bimal; Alvey Christine; Gong Jason et al. Effects of fesoterodine on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers. British journal of clinical pharmacology (2011), 72(2), 257-62.
[4]. Michel MC. Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome. Expert Opin Pharmacother. 2008 Jul;9(10):1787-96.
[5]. Fesoterodine