Capreomycin Sulfate

A polypeptide antibiotic

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库存: 现货

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50mg

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货号: ajci16638
CAS: 1405-37-4
别名: 硫酸卷曲霉素
分子式: C25H44N14O7.H2SO4
分子量: 750.78
纯度: >98%
溶解度: ≥ 251.8mg/mL in Water, <7.51mg/mL in DMSO
储存: Store at -20°C
库存: 现货

Background

Capreomycin sulfate is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis.IC50 value:Target: The drug should not be given with streptomycin or other drugs that may damage the auditory vestibular nerve. Patients on this drug will often require audiology tests. It is a cyclic peptide.Capreomycin is administered intramuscularly and shows bacteriostatic activity.

参考文献:
[1]. Johansen SK, et al. Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell. 2006 Jul 21;23(2):173-82.