4-HQN

A heterocyclic building block

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50mg

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货号: ajci17190
CAS: 491-36-1
别名: 4-羟基喹唑啉
分子式: C8H6N2O
分子量: 146.15
纯度: >98%
溶解度: ≥ 55.6mg/mL in DMSO, ≥ 4.55 mg/mL in EtOH with ultrasonic and warming
储存: Desiccate at RT
库存: 现货

Background

4(3H)-Quinazolinone is a building block in chemical synthesis. Biologically active nitrogen heterocyclic compounds. Possesses a wide spectrum of biological properties like antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancerous and analgesic activities[1][2].

参考文献:
[1]. Jafari E, et al. Quinazolinone and quinazoline derivatives: recent structures with potent antimicrobial and cytotoxic activities. Res Pharm Sci. 2016 Jan-Feb;11(1):1-14.
[2]. Hameed A, et al. Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011-2016). Expert Opin Ther Pat. 2018 Apr;28(4):281-297.