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  • Rimantadine
Rimantadine的可视化放大

Rimantadine

A derivative of amantadine with antiviral activity

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Rimantadine的二维码
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  • 25mg
    ¥600.00
    480.00
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    ¥1025.00
    820.00
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  • 货号: ajci19880
  • CAS: 13392-28-4
  • 别名: 金刚乙胺; 1-Rimantadine
  • 分子式: C12H21N
  • 分子量: 179.3
  • 纯度: >98%
  • 溶解度: DMSO : 33mg/mL; Water : 33mg/mL
  • 储存: Store at -20°C
  • 库存: 现货

Background

Rimantadine (Flumadine) is an anti-influenza virus drug.Target: Influenza Virusrimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. rimantadine has prophylactic efficacy comparable to amantadine but lower potential for causing adverse effects [1]. double-blind study of children with influenza-like illness. 37 received rimantadine for five days. Of the total 37 children in the rimantadine group, 27% were found to have resistant isolated compared with 6% in the total group receiving acetaminophen (P < .04). Furthermore, the mean inhibitory concentration of rimantadine increased with time in the rimantadine group (r = .4, P = .002) [2].


参考文献:
[1]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78.
[2]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82.

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