Clindamycin

A lincosamide antibiotic

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库存: 现货

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包装

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促销价

数量
50mg

￥600.00

480.00

- +
250mg

￥1900.00

1520.00

- +
1g

￥5287.00

4230.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Clindamycin is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1].

参考文献:
[1]. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38.