Thymoquinone

A natural anti-cancer phytochemical

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5g

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880.00

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25g

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货号: ajci20556
CAS: 490-91-5
别名: 百里醌
分子式: C10H12O2
分子量: 164.2
纯度: >98%
溶解度: DMF: 16 mg/ml,DMSO: 14 mg/ml,Ethanol: 16 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
储存: 4°C, protect from light
库存: 现货

Background

The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer.1 Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa.1 It has anti-inflammatory effects, blocking the synthesis of leukotrienes.2,1 Thymoquinone inhibits the growth of leukemia cells (IC50 = 1.5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.3 In addition to blocking cell proliferation and triggering apoptosis, thymoquinone (15 μM) suppresses STAT3-regulated gene expression and prevents angiogenesis.4,5