安捷凯生物医药
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  • CAY10452
CAY10452的可视化放大

CAY10452

A non-apoptotic, selective COX-2 inhibitor

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CAY10452的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 5mg
    ￥337.00
    270.00
    - +
  • 10mg
    ￥550.00
    440.00
    - +
  • 25mg
    ￥987.00
    790.00
    - +
  • 50mg
    ￥1625.00
    1300.00
    - +
  • 100mg
    ￥2725.00
    2180.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci21096
  • CAS: 170569-87-6
  • 别名: 塞来昔布杂质3
  • 分子式: C16H12F3N3O2S
  • 分子量: 367.3
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:8): .1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2. However, many COX inhibitors also show an antitumor, pro-apoptotic activity that is distinct from COX inhibition - celecoxib is an example. CAY10452 is a celecoxib analog that retains potent, selective COX-2 inhibitory activity (IC50 = 32 nM), but does not induce apoptosis in prostate cancer cell lines even at 100 uM. CAY10452 is thus a clean, selective tool for the inhibition of COX-2.

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