Cardanol monoene

An inhibitor of tyrosinase with anticancer properties

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
500ug

￥762.00

610.00

- +
1mg

￥1450.00

1160.00

- +
5mg

￥6437.00

5150.00

- +
10mg

￥10887.00

8710.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci21140
CAS: 501-26-8
别名: 腰果酚(C15:1),Cardanol C15
分子式: C21H34O
分子量: 302.5
纯度: >98%
溶解度: DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 22 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
储存: Store at -20°C
库存: 现货

Background

Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 uM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 uM after 24 and 48 hours of treatment, respectively). Cardanol monoene also induces apoptosis via the intrinsic pathway following the accumulation of reactive oxygen species (ROS). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.