Cyclo(L-Leu-L-Trp)

A diketopiperazine metabolite

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥4087.00

3270.00

- +
25mg

￥14175.00

11340.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria (MICs = 125-1000 ug/ml) and fungi (MICs = 8-64 ug/ml), and it inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 uM). Cyclo(L-Leu-L-Trp) is a bitter tastant that can rapidly permeate rat taste cell membranes ex vivo when used at a concentration of 1 mM. It also acts as a melatonin receptor agonist in X. laevis melanophores, inhibiting cAMP accumulation when used at a concentration of 20 uM, an effect that is blocked by the melatonin receptor antagonist luzindole .